MICRONIZERS SERIES MICRONETTE
Fluid jet mills for micronization
  Chemical
  Pharmaceutical
  Cosmetic
  Food
Among the various milling systems currently known the fluid jet mills, are the most suitable for the treatment of chemical / pharmaceutical products, but are also widely used in the cosmetic, agrochemical and food sectors.
This type of mill, thanks to its particular operating principle, allows to satisfy multiple granulometric requests until obtaining, without the aid of grinding and classifying organs, 100% micronized particles lower than 5 microns; the latter result not obtainable with conventional mills of different conception.
The fluid jet micronizer also guarantees the drastic reduction of pollution from metal parts.
For the use in the micronization of substances for pharmaceutical use it has been designed and manufactured a specific "Sanitary Version", characterized by a rapid disassembly without the aid of mechanical tools and special precautions, the equipment is easily accessible in all its parts , allowing thorough cleaning, these factors combined with the operating principle of the fluid jet mill allow the purity of the substance to be maintained unaltered.
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Micronize with the
fluid jet mill

The prevailing technology for the micronization process is represented by spiral fluid jet mills.

The operating principle does not include the use of grinding elements, since the reduction occurs exclusively by impact between the product particles, introduced into the micronization chamber, in a circular shape, through a Venturi injector. The particles are rapidly accelerated by a flow of gas (compressed air, nitrogen, argon or steam) injected through nozzles located at the periphery of the micronization chamber and are dragged in a vortical motion that causes them to collide repeatedly, progressively reducing their diameter and the mass as long as the energy accumulated by them falls to negligible values.

The micronized product particles are conveyed by the gaseous flow to a special separator cyclone filter, composed of a lower conical section, where the product is collected, and an upper cylindrical section, inside which a set of filter modules is housed, made of special fabric, which allows the exhaust of dusted air, while the finer micronized product is retained on the external surface of the same. The shaking of the filter modules takes place by means of a timed system with a counter-jet of compressed gas, which allows the removal of the micronized which is also collected in the lower conical part of the cyclone, allowing a high level of product recovery and optimal process efficiency of the system. For particular applications, such as integrated configurations in glove box isolator or, on specific request, octopus filter systems realized with inverted sleeves and pneumatic shaking.

Advantages of the micronization technology
THE MAIN ADVANTAGES OF THIS TECHNOLOGY ARE REPRESENTED BY:
  • No lubrication required
  • significant reduction in metal contamination
  • Easy cleaning of components
  • significant reduction of cross contamination
  • Constant process temperature, no heat generation (Joule-Thomson effect)
  • preservation of product characteristics
  • possibility of treating heat sensitive products
Characteristics of micronization
Micronization is a cutting-edge technique that allows to reduce the particle size of a powder substance down to micrometric dimensions, which is used in various sectors such as, for example: pharmaceutical, chemical, cosmetic and food.
The advantage of a micronized powder is linked to the increase in the surface of the product: a higher exposed surface allows greater availability of the molecule in the reference process, a factor of fundamental importance, especially in the pharmaceutical field (bioavailability).
MODELS AND DATASHEETS

I mulini micronizzatori nuova guseo si sviluppano tramite una gamma di macchine che comprendono sia le versioni da laboratorio fino ai modelli industriali.

MODEL
M100
Diametro nominale :
100 mm
Capacità stimata :
Da 0.05 a 5 kg/h
Lotto di lavoro suggerito :
Da 0.05 a 10 kg
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
20 Nm3/min.
MODEL
M200
Diametro nominale :
200 mm
Capacità stimata :
Da 1 a 40 kg/h
Lotto di lavoro suggerito :
Da 1 a 100 kg
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
100 Nm3/min.
MODEL
M300
Diametro nominale :
300 mm
Capacità stimata :
Da 5 a 80 kg/h
Lotto di lavoro suggerito :
Da 10 a 1000 kg
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
240 Nm3/min.
MODEL
M400
Diametro nominale :
400 mm
Capacità stimata :
Da 10 a 150 kg/h
Lotto di lavoro suggerito :
Da 10 a 3000 kg
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
600 Nm3/min.
MODEL
M500
Diametro nominale :
500 mm
Capacità stimata :
Da 100 a 300 kg/h
Lotto di lavoro suggerito :
min 100Kg - illimitato
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
760 Nm3/min.
MODEL
M600
Diametro nominale :
600 mm
Capacità stimata :
Da 100 a 500 kg/h
Lotto di lavoro suggerito :
da 100Kg sino ad un max di 5000Kg
Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
1400 Nm3/min.
MODEL
M700
Diametro nominale :
700 mm
Capacità stimata :
Da 100 a > 5000 kg/h
Lotto di lavoro suggerito :

Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
2300 Nm3/min.
MODEL
M900
Diametro nominale :
900 mm
Capacità stimata :
Da 200 a > 5000 kg/h
Lotto di lavoro suggerito :

Finezza Raggiungibile :
<5 µm *
Consumo gas di processo a 7 barg
3400 Nm3/min.

TECHNICAL DATA AND PRODUCTIVITY INDICES
The technical data and the productivity indices listed are purely indicative and may vary, even substantially, according to the product treated and the process requirements. for the aforementioned reasons it is always advisable to contact the company for more detailed information by submitting your projects / needs to our technicians so that we can advise and serve you in the best possible way.

SCHEDA COMPARATIVA M 100 M 200 M 300 M 400 M 500 M 700 M 900
 
Diametro nominale: 100mm 200mm 300mm 300mm 600mm 750mm 900mm
Capacità stimata: da 0.05 a 5 kg/h da 1 a 40 kg/h da 5 a 80 kg/h da 10 a 150 kg/h da 100 a 500 kg/h da 100 > 5000 kg/h da 200 > 5000 kg/h
Lotto di lavorazione suggerito: da 0.05 a 10 kg da 1 a 100 kg da 10 a 1000 kg da 10 a 3000 kg da 100 a 5000 kg
Finezza raggiungibile: <5 µm * <5 µm * <5 µm * <5 µm * <5 µm * <5 µm * <5 µm *
Consumo gas di processo 1 7 barg: 20 Nm3/h. 100 Nm3/h. 240 Nm3/h. 600 Nm3/h. 1400 Nm3/h. 2300 Nm3/h. 3400 Nm3/h.
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EQUIPMENTS AND POSSIBLE CONFIGURATIONS
Nuova Guseo systems are the result of know-how and experience acquired in more than 100 years of activity. This allows us to develop cutting-edge innovations and technical solutions.
Micronizers: Easy and simple disassembly for cleaning and maintenance activities
All models of micronizer are specially designed to simplify cleaning and maintenance thanks to simple and easy disassembly.
Particularly relevant is the "Sanitary Version", characterized by a quick disassembly without the aid of mechanical tools and particular precautions, the equipment is easily accessible in all its parts, allowing an accurate cleaning. These factors, combined with the operating principle of the fluid jet mill, make it possible to maintain the purity of the substance unaltered.
Laboratory / pilot scale micronizers
These two versions, M50, with product discharge from the lower plate of the micronization chamber, and M100, are the smallest versions of the entire range of systems and are specifically designed for laboratory use and for the treatment of small batches of product.
Cyclone filter system with 90 ° rotation
FILTERING SYSTEMS of particular interest is the configuration of the cyclone filter equipped with a device for rotating the filter by 90 °, which guarantees easy accessibility inside the device in order to facilitate the extraction of the bags and the subsequent cleaning of the cone, avoiding the in this way, the use of access ramps or elevators. In case of treatment of active products, the sleeves can be extracted through an accessory (supplied separately) consisting of a sight glass equipped with gloves, to be installed on the upper part of the filter, thus ensuring less exposure of the operator to dust. This configuration is mainly used in the chemical-pharmaceutical field for production models up to size M400.


For laboratory / pilot scale equipment, special bag filtering devices are provided, installed directly at the top of the micronization chamber in the case of the M50, within a specific integrated system with product collection container or with cyclone filter and discharging valve for the M100, the sleeves are equipped with a pneumatic or manual shaking system.
Micronizer integrated in containment system for treatment of highly active products
The issue of containment is of ever-increasing importance in the chemical-pharmaceutical field, especially in relation to the increased toxicity of the products treated, such as API (Active Pharmaceutical Ingredient) and especially HAPI (Highly Active Pharmaceutical Ingredient). The need to perform various process steps in a confined environment, for reasons of safety and protection of operators, the product and the environment, necessarily also concerns the micronization process of active ingredients. We are talking about configurations suitable for installation in the isolator, typically a multi-chamber system, where the main chamber houses the jetmill, equipped with a feeder in a "wall mounted" configuration, i.e. with the motor installed outside the isolator, to optimize operating space and facilitate the cleaning activities. The main chamber is connected to the gas-solid separation chamber, articulated in an upper section with installed the filtration system, usually octopus type, and the lower section for the discharge and outlete of the product in safe conditions. For configurations with pilot or laboratory scale mills, the process is contained in a single processing chamber, with possible product inlet pre-chamber, keeping the protection requirements and the effectiveness of the process unaltered.
MICRONIZATION IN CLOSED CYCLE OF INERT GAS (ONLY ON M200-M300-M400-M500-M600 MODELS)
Directive 2014/34 EU (Atex)
For use in classified areas (with the presence of hazardous gas and / or dust mixtures) the equipment is manufactured in compliance with the 2014/34 EU Directive.
MICRONIZER WITH THE POSSIBILITY OF CUSTOMIZATION FOR POSSIBLE PROCESS REQUIREMENTS
FOR SPECIFIC PROCESS REQUIREMENTS:
  • Possible variation of the number, diameter and configuration of the micronizing nozzles
  • Possible variation of the diameter and position of the injector, possible variation of the Venturi diameter
MICRONIZATION PLANTS WITH PRODUCT LOADING AND UNLOADING ADAPTABLE TO PROCESS REQUIREMENTS
MICRONIZATION PLANTS WITH MAIN PANEL AND HMI MADE AND POSITIONED IN RELATION TO THE CHARACTERISTICS OF THE INSTALLATION AREA
MICRONIZATION SYSTEMS WITH POSSIBLE IMPLEMENTATION WITH FINAL FILTRATION UNIT INTERFACED WITH THE CYCLONE FILTER
IN-LINE SAMPLING DEVICE APPLICABLE TO MICRONIZATION PLANTS
the execution of in-line product sampling activities is frequently required especially for chemical-pharmaceutical applications, with the main purpose of verifying "in process" the compliance of the micronized product with the required requirements, with primary reference to the particle size distribution. In fact, on the basis of the analyzes carried out on the processed product, the correctness of the set process parameters, mainly flow rate and micronization pressure, can be verified, evaluating the need to modify them. The samplers, generally located near the discharging bottom of the cyclone filter, are available in two versions; manually or pneumatically operated, both equipped with an extraction screw and a special container.
MICRONIZERS WITH INSERTS / COATINGS IN DIFFERENT MATERIALS FOR SPECIFIC PROCESS REQUIREMENTS (Sticky products, abrasives, etc.)
FOR PROCESS REQUIREMENTS IT IS POSSIBLE TO DEVELOP MICRONIZATION PLANTS WITH VARIOUS TYPES OF COATINGS/INSERTS IN DIFFERENT MATERIALS SUCH AS:
  • PTFE
  • Alumina
  • Vulkollan
  • Tungsten carbide
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